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What is the evidence for proprioceptive exercise in the treatment of osteoarthritis of the knee?

Summary

Patient Population:

N=560 (357 female). Mean age = 63 years (±1.8). All but one study excluded individuals with extreme degenerative changes.  (mostly K-L grade II or III).

Intervention:

All interventions were weight bearing, and based on functional activities (stepping, standing, walking and balancing). Exercise programs were conducted for 4-8 weeks.

Comparison:

7 studies compared the use of proprioceptive exercise to non-proprioceptive exercise. 3 studies included a comparison to a no-treatment control group. There were 7 studies selected for inclusion in the review – all were RCTs. Total PEDro scores ranged from 7-9. The greatest limitation noted by the authors was small sample size of the primary studies – all but three cohorts were underpowered and not informed by a sample size calculation. In addition, few studies reported between group differences.

Outcome:

  1. Function: proprioceptive exercise vs. no treatment – significant difference in favour of exercise at 8 weeks (MD=-12.19; 95% CI-15.67 to -8.71).
  2. Pain: proprioceptive exercise vs. no treatment – significant difference in favour of exercise at 8 weeks (p<0.01).
  3. Proprioceptive exercise vs. strengthening exercise: No significant difference in function.
  4. Proprioceptive exercise vs. general exercise: No significant difference in function or pain.

Guideline Recommendations

Source Recommendation
ACR (2019) Conditionally recommended

Outcomes Assessed

  • Benefit
  • Harm
  • Inconclusive

Proprioceptive Exercise vs. No Treatment

Function

Pain

Proprioceptive vs. Strengthening Exercise

Function

Proprioceptive vs. General Exercise

Function

Pain

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