Injection

• September 12, 2025

  What is the evidence for symptom reduction and functional improvements after corticosteroid injections in patients with carpal tunnel syndrome?

  Local corticosteroid injection vs placebo for carpal tunnel syndrome. Ashworth NL, Bland JDP, Chapman KM, Tardif G, Albarqouni L, Nagendran A. Local corticosteroid injection versus placebo for carpal tunnel syndrome. Cochrane Database Syst Rev. 2023 Feb 1;2(2):CD015148. doi: 10.1002/14651858.CD015148. PMID: 36722795; PMCID: PMC9891198.
• September 3, 2025

  What is the evidence for radiofrequency ablation for facet joint and sacroiliac joint related lower back pain?

  Xu B, Zhao X, Zhang L, Feng S, Li J, Xu Y. Radiofrequency vs Steroid Injections for Spinal Facet and Sacroiliac Joint Pain: A Systematic Review and Meta-Analysis. J Pain Res. 2024 Sep 4;17:2903-2916. doi: 10.2147/JPR.S469615. PMID: 39247173; PMCID: PMC11380878.
• August 20, 2025

  What is the evidence for suprascapular nerve blocks in patients with chronic shoulder pain for pain reduction and functional improvement?

  Yang F, Li X, Wang J, Gao Q, Pan M, Duan Z, Ren C, Guo P, Zhang Y. Efficacy of different analgesic strategies combined with conventional physiotherapy program for treating chronic shoulder pain: a systematic review and network meta-analysis. J Orthop Surg Res. 2024 Sep 6;19(1):544. doi: 10.1186/s13018-024-05037-8. PMID: 39238008; PMCID: PMC11378570.
• August 19, 2025

  What is the evidence for viscosupplementation injections of hyaluronic acid to reduce pain in patients with osteoarthritis of the shoulder?

  Familiari F, Ammendolia A, Rupp MC, Russo R, Pujia A, Montalcini T, Marotta N, Mercurio M, Galasso O, Millett PJ, Gasparini G, de Sire A. Efficacy of intra-articular injections of hyaluronic acid in patients with glenohumeral joint osteoarthritis: A systematic review and meta-analysis. J Orthop Res. 2023 Nov;41(11):2345-2358. doi: 10.1002/jor.25648. Epub 2023 Jun 26. PMID: 37314198.
• August 18, 2025

  What is the evidence for Genicular Nerve Blocks in patients with knee osteoarthritis for pain reduction?

  Vilchez-Cavazos F, Gamboa Alonso AA, Simental-Mendía M, Peña-Martínez VM, Acosta-Olivo CA, Villarreal-Villarreal GA. Genicular Nerve Block for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Clin J Pain. 2024 Oct 1;40(10):618-624. doi: 10.1097/AJP.0000000000001240. PMID: 39143682.
• December 7, 2024

  What is the evidence for the use of Platelet-Rich Plasma (PRP) injection in knee meniscal repair?

  Li Z, Weng X. Platelet-rich plasma use in meniscus repair treatment: a systematic review and meta-analysis of clinical studies. J Orthop Surg Res. 2022 Oct 8;17(1):446. doi: 10.1186/s13018-022-03293-0. PMID: 36209223; PMCID: PMC9548158.
• November 13, 2020

  What is the evidence for corticosteroid injection for Greater Trochanteric Pain Syndrome (Hip)?

  Barratt PA, Brookes N, Newson A. Conservative treatments for greater trochanteric pain syndrome: a systematic review. Br J Sports Med. 2017 Jan;51(2):97-104. doi: 10.1136/bjsports-2015-095858. Epub 2016 Nov 10. PMID: 27834675.
• September 21, 2019

  What is the evidence for corticosteroid injections for trigger finger?

  Huisstede BM, Gladdines S, Randsdorp MS, Koes BW. Effectiveness of Conservative, Surgical, and Postsurgical Interventions for Trigger Finger, Dupuytren Disease, and De Quervain Disease: A Systematic Review. Arch Phys Med Rehabil. 2018 Aug;99(8):1635-1649.e21. PubMed PMID: 28860097.
• August 24, 2018

  What is the evidence for injections (corticosteroid, viscosupplementation, PRP) for arthritis of the ankle?

  Vannabouathong C, Del Fabbro G, Sales B, Smith C, Li CS, Yardley D, Bandari M, Petrisor BA; EnCORE Research Group. Intra-articular Injections in the Treatment of Symptoms from Ankle Arthritis: A Systematic Review. Foot Ankle Int. 2018 Jun 1:1071100718779375. doi: 10.1177/1071100718779375. [Epub ahead of print] PubMed PMID: 29909689
• February 3, 2017

  What is the evidence for intra-articular PRP (Platelet rich plasma) injection for knee osteoarthritis?

  Dai, W. L., Zhou, A. G., Zhang, H., & Zhang, J. (2016). Efficacy of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Meta-analysis of Randomized Controlled Trials. Arthroscopy. doi: 10.1016/j.arthro.2016.09.024
• July 5, 2016

  What is the evidence for corticosteroid injection to treat osteoarthritis of the femoral-acetabular (Hip) joint?

  McCabe PS, et al., The efficacy of intra-articular steroids in hip osteoarthritis: a systematic review, Osteoarthritis and Cartilage (2016), http://dx.doi.org/10.1016/j.joca.2016.04.018
• March 22, 2016

  What is the evidence for prolotherapy for achilles tendinopathy?

  Sanderson LM, Bryant A, "Effectiveness and safety of prolotherapy injections for management of lower limb tendinopathy and fasciopathy: a systematic review", J Foot Ankle Res., 2015 Oct 25, 8:57.
• May 26, 2015

  What is the evidence for conservative (non-surgical) measures to treat carpal tunnel syndrome?

  Huisstede BM1, Hoogvliet P, Randsdorp MS, Glerum S, van Middelkoop M, Koes BW. Carpal tunnel syndrome. Part I: effectiveness of nonsurgical treatments--a systematic review., Arch Phys Med Rehabil. 2010 Jul;91(7):981-1004.
  
• November 30, 2014

  What is the evidence for PRP injection for the treatment of soft tissue injuries?

  Moraes, V. Y., M. Lenza, M. J. Tamaoki, F. Faloppa and J. C. Belloti (2014). "Platelet-rich therapies for musculoskeletal soft tissue injuries." Cochrane Database Syst Rev 4: CD010071.
• November 30, 2014

  What is the evidence for trigger point injections for myofascial pain?

  Scott, N. A., B. Guo, P. M. Barton and R. D. Gerwin (2009). "Trigger point injections for chronic non-malignant musculoskeletal pain: a systematic review." Pain Med 10(1): 54-69.
• November 2, 2014

  What is the evidence for epidural injections for spinal stenosis?

  Ramsin M. Benyamin, MD, et al., The Effectiveness of Lumbar Interlaminar Epidural Injections in Managing Chronic Low Back and Lower Extremity Pain, Pain Physician 2012; 15:E363-E404
• August 5, 2014

  What is the evidence for EDTA in the treatment of subacromial impingement syndrome?

  Van Der Sande, R., et al. (2013). "Subacromial impingement syndrome: Effectiveness of pharmaceutical interventions-nonsteroidal anti-inflammatory drugs, corticosteroid, or other injections: A systematic review." Archives of Physical Medicine and Rehabilitation 94(5): 961-976.
• August 5, 2014

  What is the evidence for tenoxicam injections in the treatment of subacromial impingement syndrome?

  Van Der Sande, R., et al. (2013). "Subacromial impingement syndrome: Effectiveness of pharmaceutical interventions-nonsteroidal anti-inflammatory drugs, corticosteroid, or other injections: A systematic review." Archives of Physical Medicine and Rehabilitation 94(5): 961-976.
• August 5, 2014

  What is the evidence for corticosteroid injections in the treatment of rotator cuff pathology?

  Koester, M. C., et al. (2007). "The efficacy of subacromial corticosteroid injection in the treatment of rotator cuff disease: A systematic review." Journal of the American Academy of Orthopaedic Surgeons 15(1): 3-11.
• August 5, 2014

  What is the evidence for corticosteroid injections in the treatment of osteoarthritis of the shoulder?

  Gross, C., et al. (2013). "Glenohumeral Joint Injections: A Review." Sports Health 5(2): 153-159.
• August 5, 2014

  What is the evidence for viscosupplementation in the treatment of adhesive capsulitis?

  Maund, E., et al. (2012). "Management of frozen shoulder: A systematic review and cost-effectiveness analysis." Health Technology Assessment 16(11): i-xvi+1-243.
• August 5, 2014

  What is the evidence for improving the accuracy of knee injections?

  Daley, E. L., et al. (2011). "Improving injection accuracy of the elbow, knee, and shoulder: does injection site and imaging make a difference? A systematic review." Am J Sports Med 39(3): 656-662.
• August 5, 2014

  What is the evidence for ultrasound guided injection for the treatment of shoulder pathology?

  Sage, W., et al. (2013). "The clinical and functional outcomes of ultrasound-guided vs landmark-guided injections for adults with shoulder pathology-a systematic review and meta-analysis." Rheumatology 52(4): 743-751.
• August 5, 2014

  What is the evidence for pharmacotherapy in the treatment of patellofemoral pain syndrome?

  Heintjes, E., et al. (2004). "Pharmacotherapy for patellofemoral pain syndrome." Cochrane Database Syst Rev(3): CD003470.
• July 25, 2014

  What is the evidence for corticosteroid injections in the treatment of osteoarthritis of the knee?

  Jüni P, Hari R, Rutjes AW, Fischer R, Silletta MG, Reichenbach S, da Costa BR. Intra-articular corticosteroid for knee osteoarthritis. Cochrane Database Syst Rev. 2015 Oct 22;(10):CD005328. doi: 10.1002/14651858.CD005328.pub3. PMID: 26490760.
• July 24, 2014

  What is the evidence for botulinum toxin is the treatment of shoulder pain?

  Singh Jasvinder, A. and M. Fitzgerald Patrick (2010) Botulinum toxin for shoulder pain. Cochrane Database of Systematic Reviews DOI: 10.1002/14651858.CD008271.pub2
• July 21, 2014

  What is the evidence for corticosteroid injections in the treatment of subacromial impingement syndrome?

  Van Der Sande, R., et al. (2013). "Subacromial impingement syndrome: Effectiveness of pharmaceutical interventions-nonsteroidal anti-inflammatory drugs, corticosteroid, or other injections: A systematic review." Archives of Physical Medicine and Rehabilitation 94(5): 961-976.
• July 21, 2014

  What is the evidence for viscosupplementation injection in treating osteoarthritis of the knee?

  Rutjes, A. W. S., et al. (2012). "Viscosupplementation for Osteoarthritis of the Knee: A Systematic Review and Meta-analysis." Annals of Internal Medicine 157(3): 180-191.
• July 21, 2014

  What is the evidence for corticosteroid injections in treating adhesive capsulitis?

  Maund, E., et al. (2012). "Management of frozen shoulder: A systematic review and cost-effectiveness analysis." Health Technology Assessment 16(11): i-xvi+1-243.