What is the evidence for Topical Glyceryl Trinitrate (Nitro patch) for the treatment of Patellar Tendinopathy
AMSTAR Rating
Summary
Patient Population:
- 1 study (33 participants) reviewed the effect of glyceryl trinitrate patches for tendinopathy
- Median age 32.9 years (> 18 years old)
Intervention:
- Glyceryl trinitrate patch (dosage 1.25mg/day) plus rehab for 12 weeks
Comparison:
- Placebo patch plus rehab
Outcome:
- No significant differences in short term (6 and 12 weeks) or midterm (24 weeks) outcomes between patients receiving GTN or placebo (Level 3 evidence)
- Outcomes included Pain with sport, VISA-P questionnaire, and Patient Satisfaction
Outcomes Assessed
- Benefit
- Harm
- Inconclusive
Pain with sport
Short term (6 weeks)
Midterm (24 weeks)
Patient Satisfaction
Short term
Midterm
VISA-P Questionnaire
Short term
Midterm
Common Side Effects
Rash (19%)
Relevant Clinical Info
Results based on a single small RCT by Steunebrink et al. (Br J Sports Med 2013;47:34–9) showed both groups improved from baseline but there was no significant difference between the treatment and control group.
*VISA-P Questionnaire is a Patellar specific outcome scale with questions focussed on impact of patellar pain on general function and sport participation
https://www.ouh.nhs.uk/oxsport/information/ documents/TheVISAscore.pdf
Participant Information
the sample size was 33
Mean age of 32.9 years.
their were 1 studies used.
