Quickly review your physical exam skills, and make evidence informed clinical decisions. All while earning CME Credit.

EBM Body Parts

EBM Treatments

EBM Diagnosis

  • CME Credits icon

What is the evidence for EDTA in the treatment of subacromial impingement syndrome?

Meta-Analysis

Van Der Sande, R., et al. (2013). "Subacromial impingement syndrome: Effectiveness of pharmaceutical interventions-nonsteroidal anti-inflammatory drugs, corticosteroid, or other injections: A systematic review." Archives of Physical Medicine and Rehabilitation 94(5): 961-976.
What's this
AMSTAR Rating
4

Summary

Patient Population:

A single study was identified; n=80. All participants diagnosed with calcific tendinitis.

Intervention:

Disodium ethylene diamine tetraacetic acid (EDTA) once a week for 3 weeks + 15 minutes pulsed US (1MHz) using 15% solution EDTA gel 5X/week for 3 weeks.

Comparison:

It appears that they included 3 reviews and an additional 5 RCTs that did not appear in any of those 3 reviews. From within the identified reviews, they included information from 11, 9 and 7 trials. Tables are provided reporting the information abstracted from each trial in the categories corresponding to where they were found.

Outcome:

  1. EDTA + Ultrasound (EDTA gel) vs. placebo:  Treatment was associated with significant improvements (vs. placebo) in pain and on the Constant-Murley score at 1-week and 1-year follow-up. Following treatment, less calcification was reported in the treatment group vs. placebo.
  2. Level of Evidence: The authors reported MODERATE evidence for the effectiveness of EDTA + ultrasound (with EDTA gel) vs. placebo in individuals with calcific tendinitis.

Outcomes Assessed

  • Benefit
  • Harm
  • Inconclusive

EDTA + Ultrasound (EDTA gel) vs. Placebo

Pain

CME Information / Site Feedback

Your Name (required)

Your Email (required)

1. What is the impact of this information on you or your practice?

Note: Check all that apply. You may check more than one box.

 I learned something new I am motivated to learn more This information confirmed I did (am doing) the right thing I am reassured I am reminded of something I already knew I am dissatisfied There is a problem with the presentation of this information I disagree with the content of this information This information is potentially harmful

2. Is this information relevant for at least one of your patients?

 Totally relevant Partially relevant Not relevant

3. Will you use this information for a specific patient?

 Yes No Possibly I already know about this information, and I'm Already Using it.

4. Please rate the websites ease of use.

1 2 3 4 5 

5. Likelihood of using site again/recommending the site.

1 2 3 4 5 

Additional Information

×

Example AMSTAR Information

example amstar rating guidlines example amstar rating guidlines ×
© 2024 msk medicine
disclaimer
privacy policy

mskmedicine disclaimer

Disclaimers/Terms of Use:

This project is supported by educational grants from the Schulich School of Medicine and St. Joseph’s Health Care, London, Ontario, Canada. Use of this site is for educational purposes only. Use by the end user implies agreement that the creators of the site will not be held liable in cases stemming from inaccurate information from this website. The user is encouraged to validate any information herein with an external source.  Unless otherwise stated, all research presented reflects the data of the studies referenced, and the creators/authors of this website do not take ownership or credit for this data.  The conclusions that are made from these systematic reviews reflects those of the study authors and are NOT necessarily those of the website and its editors.

×

Privacy Policy


General Statement

This policy relates to our privacy practices in connection with our website, mskmedicine.com (the “Site”). It does not describe information collection practices in relation to other websites, including those linked to or from the Site.

Your privacy is important to us, and our policy is simple. we do not collect any personal information about you when you visit the Site unless you specifically choose to provide that information.

Collection and Use of Personal Information

We do not collect any personal information about you other than that which you provide voluntarily. For example, we will retain your e-mail address if you fill out our feedback form and in order to email you your responses in regard to earning CME Credit.

Information provided by you is used solely for the purpose for which it is intended. Such information is not shared with any third party for commercial purposes.

Collection and Use of Technical information

The server on which the Site is located collects and saves only the default information normally provided by web server software. Such information may include the originating IP address, the date and time of your visit, the web pages visited on our Site and documents downloaded from it. If enabled by your web browser, the Site will place “cookies” (simple text files) on your computer so that the Site can remember you on subsequent visits. You may disable the ability of your computer to receive “cookies”.

MSK Medicine will make no attempt to identify individual visitors to the Site or associate the technical information referred to above with any individual.

This information is used only for statistical and administrative purposes and to assist mskmedicine.com in making enhancements to the visitors’ experience with the Site.

×